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1

Convergent Transcription at Intragenic Super-Enhancers Targets AID-Initiated Genomic Instability

Meng, Fei-Long, Du, Zhou, Federation, Alexander, Hu, Jiazhi, Wang, Qiao, Kieffer-Kwon, Kyong-Rim, Meyers, Robin M., Amor, Corina, Wasserman, Caitlyn R., Neuberg, Donna, Casellas, Rafael, Nussenzweig,

Journal:

Year:

2014

Language:

english

File:

PDF, 1.87 MB

english, 2014

2

CTCF orchestrates long-range cohesin-driven V(D)J recombinational scanning

Ba, Zhaoqing, Lou, Jiangman, Ye, Adam Yongxin, Dai, Hai-Qiang, Dring, Edward W., Lin, Sherry G., Jain, Suvi, Kyritsis, Nia, Kieffer-Kwon, Kyong-Rim, Casellas, Rafael, Alt, Frederick W.

Journal:

Year:

2020

File:

PDF, 9.47 MB

2020

3

Identification of Early Replicating Fragile Sites that Contribute to Genome Instability

Barlow, Jacqueline H., Faryabi, Robert B., Callén, Elsa, Wong, Nancy, Malhowski, Amy, Chen, Hua Tang, Gutierrez-Cruz, Gustavo, Sun, Hong-Wei, McKinnon, Peter, Wright, George, Casellas, Rafael, Robbian

Journal:

Year:

2013

Language:

english

File:

PDF, 1.66 MB

english, 2013

4

Somatic Rearrangement in B Cells: It’s (Mostly) Nuclear Physics

Aiden, Erez Lieberman, Casellas, Rafael

Journal:

Year:

2015

Language:

english

File:

PDF, 724 KB

english, 2015

5

Restricting activation-induced cytidine deaminase tumorigenic activity in B lymphocytes

Rafael Casellas, Arito Yamane, Alexander L. Kovalchuk, Michael Potter

Journal:

Year:

2009

Language:

english

File:

PDF, 675 KB

english, 2009

6

Safety of Single Transseptal Puncture for Ablation of Atrial Fibrillation: Retrospective Study from a Large Cohort of Patients

RAFAEL L. FAGUNDES, MASSIMO MANTICA, LUCIA DE LUCA, GIOVANNI FORLEO, AUGUSTO PAPPALARDO, ANDREA AVELLA, AURELIANO FRATICELLI, ANTONIO DELLO RUSSO, MICHELA CASELLA, GEMMA PELARGONIO, CLAUDIO TONDO

Journal:

Journal of Cardiovascular Electrophysiology

Year:

2007

Language:

english

File:

PDF, 900 KB

english, 2007

7

AID is required to initiate Nbs1/γ-H2AX focus formation and mutations at sites of class switching

Petersen, Simone, Casellas, Rafael, Reina-San-Martin, Bernardo, Chen, Hua Tang, Difilippantonio, Michael J., Wilson, Patrick C., Hanitsch, Leif, Celeste, Arkady, Muramatsu, Masamichi, Pilch, Duane R.

Journal:

Year:

2001

Language:

english

File:

PDF, 409 KB

english, 2001

8

10.1038/80816

Meffre, Eric, Casellas, Rafael, Nussenzweig, Michel C.

Journal:

Nature Immunology

Year:

2000

Language:

english

File:

PDF, 212 KB

english, 2000

9

The ATM repair pathway inhibits RNA polymerase I transcription in response to chromosome breaks

Kruhlak, Michael, Crouch, Elizabeth E., Orlov, Marika, Montaño, Carolina, Gorski, Stanislaw A., Nussenzweig, André, Misteli, Tom, Phair, Robert D., Casellas, Rafael

Journal:

Year:

2007

Language:

english

File:

PDF, 863 KB

english, 2007

10

The ATM repair pathway inhibits RNA polymerase I transcription in response to chromosome breaks

Kruhlak, Michael, Crouch, Elizabeth E., Orlov, Marika, Montaño, Carolina, Gorski, Stanislaw A., Nussenzweig, André, Misteli, Tom, Phair, Robert D., Casellas, Rafael

Journal:

Year:

2009

File:

PDF, 31 KB

2009

11

Translocation-Capture Sequencing Reveals the Extent and Nature of Chromosomal Rearrangements in B Lymphocytes

Isaac A. Klein, Wolfgang Resch, Mila Jankovic, Thiago Oliveira, Arito Yamane, Hirotaka Nakahashi, Michela Di Virgilio, Anne Bothmer, Andre Nussenzweig, Davide F. Robbiani, Rafael Casellas, Michel C. N

Journal:

Year:

2011

Language:

english

File:

PDF, 1023 KB

english, 2011

12

Translocation capture sequencing: A method for high throughput mapping of chromosomal rearrangements

Thiago Y. Oliveira, Wolfgang Resch, Mila Jankovic, Rafael Casellas, Michel C. Nussenzweig, Isaac A. Klein

Journal:

Journal of Immunological Methods

Year:

2012

Language:

english

File:

PDF, 491 KB

english, 2012

13

Reply to "Reassessing genomic targeting of AID"

Yamane, Arito, Resch, Wolfgang, Nussezweig, Michel, Casellas, Rafael

Journal:

Nature Immunology

Year:

2012

Language:

english

File:

PDF, 225 KB

english, 2012

14

Xenopus Smad7 Inhibits both the Activin and BMP Pathways and Acts as a Neural Inducer

Rafael Casellas, Ali Hemmati Brivanlou

Journal:

Developmental Biology

Year:

1998

Language:

english

File:

PDF, 14.28 MB

english, 1998

15

The In Vivo Pattern of Binding of RAG1 and RAG2 to Antigen Receptor Loci

Yanhong Ji, Wolfgang Resch, Elizabeth Corbett, Arito Yamane, Rafael Casellas, David G. Schatz

Journal:

Year:

2010

Language:

english

File:

PDF, 1.50 MB

english, 2010

16

The In Vivo Pattern of Binding of RAG1 and RAG2 to Antigen Receptor Loci

Yanhong Ji, Wolfgang Resch, Elizabeth Corbett, Arito Yamane, Rafael Casellas, David G. Schatz

Journal:

Year:

2010

Language:

english

File:

PDF, 34 KB

english, 2010

17

MicroRNA-155 Is a Negative Regulator of Activation-Induced Cytidine Deaminase

Grace Teng, Paul Hakimpour, Pablo Landgraf, Amanda Rice, Thomas Tuschl, Rafael Casellas, F. Nina Papavasiliou

Journal:

Year:

2008

Language:

english

File:

PDF, 825 KB

english, 2008

18

OcaB Is Required for Normal Transcription and V(D)J Recombination of a Subset of Immunoglobulin κ Genes

Rafael Casellas, Mila Jankovic, Gesa Meyer, Anna Gazumyan, Yan Luo, Robert G. Roeder, Michel C. Nussenzweig

Journal:

Year:

2002

Language:

english

File:

PDF, 1.11 MB

english, 2002

19

c-Myc Is a Universal Amplifier of Expressed Genes in Lymphocytes and Embryonic Stem Cells

Nie, Zuqin, Hu, Gangqing, Wei, Gang, Cui, Kairong, Yamane, Arito, Resch, Wolfgang, Wang, Ruoning, Green, Douglas R., Tessarollo, Lino, Casellas, Rafael, Zhao, Keji, Levens, David

Journal:

Year:

2012

Language:

english

File:

PDF, 2.49 MB

english, 2012

20

Deep-sequencing identification of the genomic targets of the cytidine deaminase AID and its cofactor RPA in B lymphocytes

Yamane, Arito, Resch, Wolfgang, Kuo, Nan, Kuchen, Stefan, Li, Zhiyu, Sun, Hong-wei, Robbiani, Davide F, McBride, Kevin, Nussenzweig, Michel C, Casellas, Rafael

Journal:

Nature Immunology

Year:

2011

Language:

english

File:

PDF, 1.06 MB

english, 2011

21

TGF-β and retinoic acid induce the microRNA miR-10a, which targets Bcl-6 and constrains the plasticity of helper T cells

Takahashi, Hayato, Kanno, Tomohiko, Nakayamada, Shingo, Hirahara, Kiyoshi, Sciumè, Giuseppe, Muljo, Stefan A, Kuchen, Stefan, Casellas, Rafael, Wei, Lai, Kanno, Yuka, O'Shea, John J

Journal:

Nature Immunology

Year:

2012

Language:

english

File:

PDF, 1.32 MB

english, 2012

22

53BP1 Alters the Landscape of DNA Rearrangements and Suppresses AID-Induced B Cell Lymphoma

Jankovic, Mila, Feldhahn, Niklas, Oliveira, Thiago Y., Silva, Israel T., Kieffer-Kwon, Kyong-Rim, Yamane, Arito, Resch, Wolfgang, Klein, Isaac, Robbiani, Davide F., Casellas, Rafael, Nussenzweig, Mich

Journal:

Year:

2013

Language:

english

File:

PDF, 1.30 MB

english, 2013

23

The Origin of B Cell Recurrent Chromosomal Translocations: Proximity versus DNA Damage

Casellas, Rafael, Resch, Wolfgang, Hakim, Ofir, Nussenzweig, Michel C.

Journal:

Year:

2013

Language:

english

File:

PDF, 90 KB

english, 2013

24

Epigenetic targeting of activation-induced cytidine deaminase

Wang, Qiao, Oliveira, Thiago, Jankovic, Mila, Silva, Israel T., Hakim, Ofir, Yao, Kaihui, Gazumyan, Anna, Mayer, Christian T., Pavri, Rushad, Casellas, Rafael, Nussenzweig, Michel C., Robbiani, Davide

Journal:

Proceedings of the National Academy of Sciences

Year:

2014

Language:

english

File:

PDF, 1.56 MB

english, 2014

25

RAG s and R egulation of A utoantibodies

Jankovic, Mila, Casellas, Rafael, Yannoutsos, Nikos, Wardemann, Hedda, Nussenzweig, Michel C.

Journal:

Annual Review of Immunology

Year:

2004

Language:

english

File:

PDF, 282 KB

english, 2004

26

MicroRNA-146a regulates ICOS–ICOSL signalling to limit accumulation of T follicular helper cells and germinal centres

Pratama, Alvin, Srivastava, Monika, Williams, Naomi J., Papa, Ilenia, Lee, Sau K., Dinh, Xuyen T., Hutloff, Andreas, Jordan, Margaret A., Zhao, Jimmy L., Casellas, Rafael, Athanasopoulos, Vicki, Vinue

Journal:

Nature Communications

Year:

2015

Language:

english

File:

PDF, 2.59 MB

english, 2015

27

Preferential localization of IgG memory B cells adjacent to contracted germinal centers

Yuichi Aiba, Kohei Kometani, Megumi Hamadate, Saya Moriyama, Asako Sakaue-Sawano, Michio Tomura, Hervé Luche, Hans Jörg Fehling, Rafael Casellas, Osami Kanagawa, Atsushi Miyawaki, Tomohiro Kurosaki an

Journal:

Proceedings of the National Academy of Sciences

Year:

2010

Language:

english

File:

PDF, 1.43 MB

english, 2010

28

Mutations, kataegis and translocations in B cells: understanding AID promiscuous activity

Casellas, Rafael, Basu, Uttiya, Yewdell, William T., Chaudhuri, Jayanta, Robbiani, Davide F., Di Noia, Javier M.

Journal:

Nature Reviews Immunology

Year:

2016

Language:

english

File:

PDF, 968 KB

english, 2016

29

HMGN proteins modulate chromatin regulatory sites and gene expression during activation of naïve B cells

Zhang, Shaofei, Zhu, Iris, Deng, Tao, Furusawa, Takashi, Rochman, Mark, Vacchio, Melanie S., Bosselut, Remy, Yamane, Arito, Casellas, Rafael, Landsman, David, Bustin, Michael

Journal:

Nucleic Acids Research

Year:

2016

Language:

english

File:

PDF, 5.79 MB

english, 2016

30

The cell cycle restricts activation-induced cytidine deaminase activity to early G1

Wang, Qiao, Kieffer-Kwon, Kyong-Rim, Oliveira, Thiago Y., Mayer, Christian T., Yao, Kaihui, Pai, Joy, Cao, Zhen, Dose, Marei, Casellas, Rafael, Jankovic, Mila, Nussenzweig, Michel C., Robbiani, Davide

Journal:

Journal of Experimental Medicine

Year:

2017

Language:

english

File:

PDF, 2.03 MB

english, 2017

31

Permanganate/S1 Nuclease Footprinting Reveals Non-B DNA Structures with Regulatory Potential across a Mammalian Genome

Kouzine, Fedor, Wojtowicz, Damian, Baranello, Laura, Yamane, Arito, Nelson, Steevenson, Resch, Wolfgang, Kieffer-Kwon, Kyong-Rim, Benham, Craig J., Casellas, Rafael, Przytycka, Teresa M., Levens, Davi

Journal:

Year:

2017

Language:

english

File:

PDF, 3.37 MB

english, 2017

32

Partition of Myc into Immobile vs. Mobile Complexes within Nuclei

Rosales, Tilman, Nie, Zuqin, Kapoor, Varun, Casellas, Rafael, Knutson, Jay R., Levens, David

Journal:

Scientific Reports

Year:

2013

Language:

english

File:

PDF, 1.01 MB

english, 2013

33

Isolated aphasia in the emergency department: The likelihood of ischemia is low

Casella, Gabriel, Llinas, Rafael H., Marsh, Elisabeth B.

Journal:

Clinical Neurology and Neurosurgery

Year:

2017

Language:

english

File:

PDF, 150 KB

english, 2017

34

The Reign of Antibodies: A Celebration of and Tribute to Michael Potter and His Homogeneous Immunoglobulin Workshops

Gearhart, Patricia J., Mock, Beverly A., Casellas, Rafael, Cancro, Michael P.

Journal:

The Journal of Immunology

Year:

2018

Language:

english

File:

PDF, 977 KB

english, 2018

35

Epigenetic silencing of miR-125b is required for normal B cell development

Li, Guideng, So, Alex Yick-Lun, Sookram, Reeshelle, Wong, Stephanie, Wang, Jessica K., Ouyang, Yong, He, Peng, Su, Yapeng, Casellas, Rafael, Baltimore, David

Journal:

Year:

2018

Language:

english

File:

PDF, 1.01 MB

english, 2018

36

Fate Mapping for Activation-Induced Cytidine Deaminase (AID) Marks Non-Lymphoid Cells During Mouse Development

Rommel, Philipp C., Bosque, David, Gitlin, Alexander D., Croft, Gist F., Heintz, Nathaniel, Casellas, Rafael, Nussenzweig, Michel C., Kriaucionis, Skirmantas, Robbiani, Davide F., Fugmann, Sebastian D

Journal:

Year:

2013

Language:

english

File:

PDF, 1.77 MB

english, 2013

37

Multicenter, Randomized Clinical Trial to Assess the Effectiveness of Intravitreal Injections of Bevacizumab, Triamcinolone, or Their Combination in the Treatment of Diabetic Macular Edema

Neto, Hermelino O., Regatieri, Caio V., Nobrega, Mário J., Muccioli, Cristina, Casella, Antonio M., Andrade, Rafael E., Maia, Mauricio, Kniggendorf, Vinicius, Ferreira, Magno, Branco, André C., Belfor

Journal:

Ophthalmic Surgery, Lasers and Imaging Retina

Year:

2017

Language:

english

File:

PDF, 581 KB

english, 2017

38

Endovascular treatment of peripheral arterial injury with covered stents: an experimental study in pigs

Belczak, Sergio, Silva, Erasmo Simião da, Aun, Ricardo, Sincos, Igor Rafael, Belon, Alessandro Rodrigo, Casella, Ivan Benaduce, Gornati, Vitor, Figueiredo, late Luiz Francisco Poli de

Journal:

Year:

2011

Language:

english

File:

PDF, 762 KB

english, 2011

39

Endovascular and open repair for blunt aortic injury, treated in one clinical institution in Brazil: a case series

Sincos, Igor Rafael, Aun, Ricardo, Belczak, Sergio Quilici, Nascimento, Luciano Dias, Mioto Netto, Boulanger, Casella, Ivan, Silva, Erasmo Simao da, Puech-Leão, Pedro

Journal:

Year:

2011

Language:

english

File:

PDF, 2.44 MB

english, 2011

40

Gain of CTCF-anchored chromatin loops marks the exit from naive pluripotency

Pękowska, Aleksandra, Klaus, Bernd, Xiang, Wanqing, Severino, Jacqueline, Daigle, Nathalie, Klein, Felix A., Oleś, Małgorzata, Casellas, Rafael, Ellenberg, Jan, Steinmetz, Lars M., Bertone, Paul, Hube

Journal:

Year:

2018

Language:

english

File:

PDF, 3.89 MB

english, 2018

41

Xenopus Smad7 inhibits both the activin and BMP pathways and acts as a neural inducer

Casellas, Rafael, Brivanlou, Ali Hemmati

Journal:

Developmental Biology

Year:

1998

Language:

english

File:

PDF, 11.49 MB

english, 1998

42

Fundamental roles of chromatin loop extrusion in antibody class switching

Zhang, Xuefei, Zhang, Yu, Ba, Zhaoqing, Kyritsis, Nia, Casellas, Rafael, Alt, Frederick W.

Journal:

Year:

2019

Language:

english

File:

PDF, 11.70 MB

english, 2019

43

Etherification of 5-hydroxymethylfurfural using a heteropolyacid supported on a silica matrix

Portilla-ZuÃ±iga, Omar M., MartÃnez, JosÃ© J., Casella, MÃ³nica, Lick, Daniela I., Sathicq, Ãngel G., Luque, Rafael, Romanelli, Gustavo P.

Journal:

Molecular Catalysis

Year:

2020

File:

PDF, 966 KB

2020